Defective in vivo induction of functional type 2 cytokine responses in aged mice
نویسندگان
چکیده
منابع مشابه
Defective pro-IL-1beta responses in macrophages from aged mice
Background: Cytokines regulated by the inflammasome pathway have been extensively implicated in various age-related immune pathologies. We set out to elucidate the contribution of the nod-like receptor protein 3 (NLRP3) inflammasome pathway to the previously described deficiencies in IL-1β production by macrophages from aged mice. We examined the production of pro-IL-1β and its conversion into ...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 2001
ISSN: 0014-2980,1521-4141
DOI: 10.1002/1521-4141(200105)31:5<1495::aid-immu1495>3.0.co;2-8